The prize: ending the Apocalypse. The price: Sam's life. Season 5's horrific finale left Dean alone, as Sam descended into Hell. Now a different man, Dean vows to stop hunting and devote himself to building a family with Lisa and her son Ben. Then, mysteriously, Sam reappears, drawing Dean back into the old life. But Sam's a different man too. He's returned without his soul. How the Winchesters confront this greatest challenge yet to their powerful bond is the troubled heart - and soul - of the profound and thrilling 22-Episode Season 6. As the brothers struggle to reunite, they must also battle deadly supernatural forces. Demons. Angels. Vampires. Shapeshifters. And a terrifying new foe called the Mother of All.

Two brothers and one fallen angel - against all the might of Satan and his army! As the Apocalypse grows closer, threatening to turn Earth into a battlefield soaked with human blood, Sam, Dean and Castiel struggle against daunting odds. New foes arise, including the Four Horsemen of the Apocalypse. Old friends depart, consumed by the fearsome wrath of Hell. Through it all, the Winchesters are targeted by demons and angels alike, who warn that each brother has a special and terrible role to play in the coming devastation. Season Five follows Sam and Dean on their most terrifying journey yet, one that may lead them to the only ally strong enough to defeat the Devil: God.

The yellow-eyed demon is vanquished, but at a terrible price. The battle that brought him down released hundreds of demons from Hell into an unsuspecting world. And it cost Sam his life. But a grief-stricken Dean made a deal with the Crossroad Demon: his soul for Sam's resurrection. Now Dean has just one year to live. One year to fight the unholy, the twisted, the ghoulish. One year to say farewell to Sam. And one year for Sam to search desperately for some way to save his brother. Mind-bending adventure awaits as the Winchester brothers continue their astonishing odyssey into the supernatural...and their personal odyssey into destiny.